Hitoshi Shirakawa Selected Research

driselase

3/2009	Adenosine, an identified active component from the Driselase-treated fraction of rice bran, is effective at improving metabolic syndrome in stroke-prone spontaneously hypertensive rats.
1/2007	The Driselase-treated fraction of rice bran is a more effective dietary factor to improve hypertension, glucose and lipid metabolism in stroke-prone spontaneously hypertensive rats compared to ferulic acid.

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Hitoshi Shirakawa Research Topics

Disease

14	Inflammation (Inflammations) 02/2022 - 04/2006
11	Stroke (Strokes) 11/2018 - 03/2006
10	Body Weight (Weight, Body) 11/2021 - 05/2008
8	Hypertension (High Blood Pressure) 11/2016 - 01/2007
7	Neoplasms (Cancer) 10/2020 - 11/2008
6	Insulin Resistance 08/2020 - 04/2012
4	Colitis 01/2022 - 01/2017
3	Osteoporosis 07/2021 - 01/2010
3	Obesity 08/2019 - 01/2016
3	Leukemia 04/2017 - 11/2007
3	Hyperglycemia 01/2016 - 12/2011
2	Hypogonadism (Hypergonadotropic Hypogonadism) 03/2021 - 06/2018
2	Hypoxia (Hypoxemia) 01/2014 - 11/2008
2	Vitamin K Deficiency 07/2011 - 10/2006
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 07/2010 - 03/2009
1	Non-alcoholic Fatty Liver Disease 02/2022
1	Neuroinflammatory Diseases 01/2022
1	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 07/2021
1	Intrahepatic Cholestasis 07/2021
1	Cholestasis 07/2021
1	Pruritus (Itching) 07/2021
1	Liver Diseases (Liver Disease) 07/2021
1	Liver Cirrhosis (Hepatic Cirrhosis) 07/2021
1	Carcinoma (Carcinomatosis) 05/2021
1	Wounds and Injuries (Trauma) 12/2020
1	Diabetes Complications 08/2020
1	Type 2 Diabetes Mellitus (MODY) 08/2020
1	Diabetes Mellitus 08/2020
1	Muscular Atrophy (Muscle Atrophy) 08/2020
1	Genomic Instability 01/2020
1	Metabolic Diseases (Metabolic Disease) 08/2019
1	Insulinoma 04/2019
1	Body Weight Changes 07/2017
1	Atherosclerosis 04/2017

Drug/Important Bio-Agent (IBA)

13	Glucose (Dextrose)FDA LinkGeneric 08/2019 - 03/2006
7	Testosterone (Sustanon)FDA Link 03/2021 - 10/2006
7	LipidsIBA 12/2020 - 03/2006
6	Vitamin K FDA Link 07/2021 - 04/2006
5	Messenger RNA (mRNA)IBA 01/2022 - 11/2008
5	menatetrenoneIBA 09/2021 - 09/2011
5	LipopolysaccharidesIBA 09/2021 - 04/2006
5	Triglycerides (Triacylglycerol)IBA 08/2019 - 03/2009
4	CytokinesIBA 01/2022 - 07/2017
4	LigandsIBA 07/2021 - 11/2007
4	Adenosine (Adenocard)FDA LinkGeneric 11/2018 - 03/2009
3	geranylgeraniolIBA 09/2021 - 04/2013
3	Dextrans (Dextran)FDA Link 05/2021 - 01/2017
3	sodium sulfate (sodium bisulfate)FDA LinkGeneric 05/2021 - 01/2017
3	Insulin (Novolin)FDA Link 11/2016 - 03/2009
3	8-Hydroxy-2'-DeoxyguanosineIBA 01/2015 - 01/2007
3	Biotin (Vitamin H)FDA Link 04/2012 - 04/2008
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2011 - 01/2007
2	ChemokinesIBA 01/2022 - 07/2017
2	Interleukin-6 (Interleukin 6)IBA 01/2022 - 01/2017
2	Vitamin K 2 (Vitamin K2)IBA 09/2021 - 05/2019
2	Pharmaceutical PreparationsIBA 07/2021 - 05/2021
2	Ethanol (Ethyl Alcohol)IBA 12/2020 - 04/2017
2	Proteins (Proteins, Gene)FDA Link 12/2020 - 11/2008
2	Progesterone FDA LinkGeneric 10/2020 - 01/2016
2	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 10/2020 - 01/2016
2	Adenosine Monophosphate (AMP)IBA 11/2018 - 12/2011
2	5-hydroxy-3,7,3',4'-tetramethoxyflavoneIBA 04/2017 - 01/2014
2	Tryptophan (L-Tryptophan)FDA Link 01/2017 - 06/2011
2	EnzymesIBA 11/2016 - 09/2011
2	AdiponectinIBA 12/2011 - 03/2009
2	Antihypertensive Agents (Antihypertensives)IBA 07/2010 - 04/2008
2	driselaseIBA 03/2009 - 01/2007
2	ferulic acid (sodium ferulate)IBA 04/2008 - 01/2007
1	InterleukinsIBA 02/2022
1	Advanced Glycation End ProductsIBA 01/2022
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2022
1	SolutionsIBA 11/2021
1	NF-kappa B (NF-kB)IBA 09/2021
1	Cholecalciferol (Vitamin D3)FDA Link 07/2021
1	Rifampin (Rifampicin)FDA LinkGeneric 07/2021
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 12/2020
1	EndotoxinsIBA 12/2020
1	Fish OilsIBA 12/2020
1	Alanine Transaminase (SGPT)IBA 12/2020
1	SulfoxidesIBA 10/2020
1	Cysteine (L-Cysteine)FDA Link 10/2020
1	Hormones (Hormone)IBA 10/2020
1	SteroidsIBA 10/2020
1	Streptozocin (Streptozotocin)FDA Link 08/2020
1	ResveratrolIBA 01/2020
1	PolyphenolsIBA 01/2020
1	Uric Acid (Urate)IBA 08/2019
1	CholesterolIBA 08/2019
1	VitaminsIBA 07/2018
1	Volatile Fatty AcidsIBA 07/2017
1	MucinsIBA 07/2017
1	Peroxidase (Myeloperoxidase)IBA 07/2017
1	tryptamineIBA 07/2017
1	AntioxidantsIBA 04/2017
1	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2017
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2017

Therapy/Procedure

5	Oral Administration 11/2016 - 04/2008
1	Ligation 07/2021
1	Therapeutics 03/2021
1	Glycemic Control 08/2020